Dr. Kriebel: Exploring Multifactorial Contributors to Disease Outcomes: Part I
Dr. Herbert: Exploring Multifactorial Contributors to Disease Outcomes: Part II
Dr. Bauer: Exploring Multifactorial Contributors to Disease Outcomes: Part III
Emerging science points to multiple and interacting factors that have the potential to disrupt developmental pathways and create susceptibilities to disease and disability. Acetaminophen, a commonly used over-the-counter medication, is already known to interfere with hepatic metabolism and is the leading cause of acute liver failure. Research suggests its toxicity may start at lower doses than previously recognized and have second-generation effects. Recent research has found that acetaminophen is also an anti-androgenic agent with the potential to affect the developing reproductive, immune and neurological systems. New studies suggest acetaminophen may be linked to the development of asthma and autism.
Aluminum is really nothing without the MERCURY!
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1 Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA 2 Internal Medicine Group Practice, PhyNet, Inc., Longview, TX 75604, USA
* Author to whom correspondence should be addressed.
Received: 24 September 2012; in revised form: 16 October 2012 / Accepted: 5 November 2012 / Published: 7 November 2012
(This article belongs to the Special Issue Biosemiotic Entropy: Disorder, Disease, and Mortality)
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Abstract: Autism is a condition characterized by impaired cognitive and social skills, associated with compromised immune function. The incidence is alarmingly on the rise, and environmental factors are increasingly suspected to play a role. This paper investigates word frequency patterns in the U.S. CDC Vaccine Adverse Events Reporting System (VAERS) database. Our results provide strong evidence supporting a link between autism and the aluminum in vaccines. A literature review showing toxicity of aluminum in human physiology offers further support. Mentions of autism in VAERS increased steadily at the end of the last century, during a period when mercury was being phased out, while aluminum adjuvant burden was being increased. Using standard log-likelihood ratio techniques, we identify several signs and symptoms that are significantly more prevalent in vaccine reports after 2000, including cellulitis, seizure, depression, fatigue, pain and death, which are also significantly associated with aluminum-containing vaccines. We propose that children with the autism diagnosis are especially vulnerable to toxic metals such as aluminum and mercury due to insufficient serum sulfate and glutathione. A strong correlation between autism and the MMR (Measles, Mumps, Rubella) vaccine is also observed, which may be partially explained via an increased sensitivity to acetaminophen administered to control fever.
BRITAIN’S most popular painkiller is at the centre of a major health scare over fears it can cause liver failure and death.
Health regulators are to limit the amount of paracetamol in prescription medicines because of soaring cases of liver damage.
Paracetamol – also known as acetaminophen – is highly toxic to the liver if taken in excessive amounts and even more dangerous at the larger doses found in prescription combination drugs.
But if taken with a second over-the-counter drug that already has high levels of paracetamol, it can kill. Paracetamol is often found in cold and flu medicines.
Now the US regulator, the Food and Drug Administration, has announced it will cap the amount of paracetamol in drugs at 325mg per capsule instead of the current 500mg.
Some prescription medicines in America contain as much as 750mg of paracetamol.
In Britain, prescription-only and over-the-counter paracetamol tablets are limited to 500mg.
People are warned not to take more than two 500mg pills in four hours and no more than eight in 24 hours. Taking more could lead to acute liver failure.
In some cases just 10g of the drug – or 20 tablets – has been linked to overdose and liver damage. Sudden liver failure, which can be caused by the drug, can lead to the brain rapidly swelling often giving doctors little chance to save people. Just days ago it emerged that ibuprofen painkillers cause an increased risk of strokes in heart disease sufferers.