Cord blood bank ‘will save lives’

Eva was saved by a donation of cord blood like that donated by baby Darcey

A scheme to store blood taken from the umbilical cords of newborns and use it to save lives has been launched.

Cord blood, like bone marrow, can help patients survive deadly diseases such as leukaemia.

For now, the Anthony Nolan Trust Cord Blood Bank can take cord blood at just one hospital, with plans for more UK collection centres.

Even so, the charity predicted the 50,000 expected donations over the next five years would prevent many deaths.

Cord blood provides a way to give a patient the ability to produce new blood cells after this has been lost through illness or aggressive treatment.

As well as patients with blood cancers, those with sickle cell disease and immune problems could benefit.

The thing about cord blood is that it’s just thrown away – but it could save someone’s life
Mark Behan
parent of cord blood patient

It contains potent “stem cells“, which, if placed back into the bone marrow, can start producing the right sort of cells.

The umbilical cord is normally thrown away after birth, so, unlike bone marrow donation, there is no discomfort or risk to the donor.

Read moreCord blood bank ‘will save lives’

Cure for deafness now within reach

Deaf people could one day have their hearing restored through a groundbreaking gene therapy technique, a new study suggests.

The transfer of a specific gene is shown today by a milestone experiment to trigger the growth of new hair cells in the inner ear – the usually irreplaceable sensory cells that pick up sound vibrations and that are lost as a result of ageing, disease, certain drugs, and by excessive exposure to loud sound.

The approach, which one day could help millions of people worldwide with deafness and inner-ear disease, is made possible by a technique that is demonstrated in the journal Nature by an American team lead by Dr John Brigande of the Oregon Hearing Research Centre, Portland, who himself is profoundly hard of hearing.

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Cells switch identity in biological breakthrough

Scientists transform one type of cell into another in living mice

Talk about an extreme makeover: Scientists have transformed one type of cell into another in living mice, a big step toward the goal of growing replacement tissues to treat a variety of diseases.

The cell identity switch turned ordinary pancreas cells into the rarer type that churns out insulin, essential for preventing diabetes. But its implications go beyond diabetes to a host of possibilities, scientists said.

It’s the second advance in about a year that suggests that someday doctors might be able to use a patient’s own cells to treat disease or injury without turning to stem cells taken from embryos.

The work is “a major leap” in reprogramming cells from one kind to another, said one expert not involved in the research, John Gearhart of the University of Pennsylvania.

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Tiny Cellular Antennae Trigger Neural Stem Cells


Tiny thread like cilia on brain cells act as sort of an antennae that directs signals telling stem cells to create new neurons. (Credit: Image courtesy of Yale University)

ScienceDaily (Aug. 25, 2008) – Yale University scientists today reported evidence suggesting that the tiny cilia found on brain cells of mammals, thought to be vestiges of a primeval past, actually play a critical role in relaying molecular signals that spur creation of neurons in an area of the brain involved in mood, learning and memory.

The cilia found on brain cells of mammals until recently had been viewed as a mysterious remnant of a distant evolutionary past, when the tiny hair-like structures were used by single-celled organisms to navigate a primordial world.

“Many neuroscientists are shocked to learn that cells in the brain have cilia. Thus it was even more exciting to show that cilia have a key function in regulating the birth of new neurons in the brain,” said Matthew Sarkisian, post doctoral fellow in the department of neurobiology and co-first author on the study.

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Stem cells apparently cure boy’s fatal disease

The treatment uses umbilical and marrow cells to help develop normal skin. Doctors say it may move his genetic disorder, recessive epidermolysis bullosa, ‘off the incurable list’ for other patients.

Using stem cells from umbilical cord blood and bone marrow, researchers have apparently cured a fatal genetic disease in a 2-year-old Minneapolis boy, which could open the door for other stem cell treatments.

For the first time in his life, Nate Liao is wearing normal clothes, eating food that has not been pureed, and playing with his siblings.

“Nate’s quality of life is forever changed,” said Dr. John Wagner of the University of Minnesota Medical School, who performed the treatment. “Maybe we can take one more disorder off the incurable list.”

(Stem cells are the cure for all disease, including cancer, thats why the elite does not want the public to know about it. – The Infinite Unknown)

Read moreStem cells apparently cure boy’s fatal disease

Tissue of dead humans to be cloned

Scientists are to be permitted to use tissue from dead people to create cloned human stem cells for research, under a legal change put forward by the government.

Health ministers have proposed that laboratories should be allowed to use stored human tissue to create cloned embryonic stem cells without the explicit consent of the tissue donor. This would allow research to be done on tissue donated for medical research as long as 30 years ago. Scientists would also be able to use cells from people who have died since they donated their tissue or who cannot be contacted.

Many laboratories have banks of stored tissue which act as DNA libraries that can play a vital role in finding cures for serious disorders such as diabetes and motor neurone disease.

Ministers have until now insisted that scientists contact tissue donors to gain explicit consent before DNA can be used to create cloned embryonic stem cells.

Leading scientists, including three Nobel prize winners, say gaining such consent is sometimes impossible because the donors have died, donated anonymously or cannot be contacted. They say the ban on using DNA without consent could hold up vital research.

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Your Burger on Biotech

Scientists serve up leaner beef, tastier cheddar and healthier ketchup

burger.jpg
The Annotated Hamburger: Photo by Colin Smale; Schnare & Stief/Getty Images; illustration: Mitch Romanowski Design

If the biotech industry has its way, ordering a hamburger might soon sound something like this: “one charbroiled cloned-beef patty, with genetically modified cheese, lab-grown bacon and vitamin-C-fortified lettuce, on a protein-spiked bun.” The burger of the future is delicious, nutritious and contains more engineering than a stealth bomber.

With the Food and Drug Administration ruling in January that meat and milk from cloned cows, pigs, goats and their offspring is safe to eat, the only thing keeping the superburger off your dinner plate is time. It will be a few years yet before cloned meat hits store shelves. Cloning the perfect (and tastiest) cow can cost upward of $15,000, which makes clones themselves too expensive to eat, so we’ll have to wait until they spawn enough offspring (the old-fashioned way) to feed the masses. Meanwhile, researchers are busy formulating all the fixings. Take a look at what science is doing for the burger, from bun to beef and everything in between.

Recipe for Burger 2.0

Vitamin Bun
After isolating a gene in wild wheat that controls protein, zinc and iron content, scientists at the University of California at Davis spliced the gene into domestic wheat, boosting nutrient content by 12 percent.

Cruelty-Free Bacon
Scientists in the Netherlands have grown minced pork in a dish by adding water, glucose and amino acids to pig stem cells. Expect artificial ground meat by 2012 and bacon within the decade.

Better Cheddar
Food engineers are boosting cheddar flavor by adding a bacterial gene that produces an enzyme that eliminates the bitter taste created during ripening.

Leaner Beef
Several companies are cloning the country’s most prized cows to produce leaner, tastier cuts of meat. Ranchers will start breeding the clones this spring, and in five years, the offspring will be ready to grill.

Healthier Ketchup
The ethanol boom is driving up the price of corn syrup, so Heinz is breeding a tomato that is 10 percent sweeter than those grown today. Look for naturally sweeter ketchup by 2010.

High-C Lettuce
By splicing rat genes into lettuce, Virginia Tech scientists figured out how to turn on the vegetable’s latent vitamin-C-producing abilities (rats are natural C-makers). Since rodent-altered lettuce is somewhat unappetizing, the team used the data to identify plant DNA that can do the same thing.

By Rena Marie Pacella Posted 03.17.2008 at 2:55 pm

Source: popsci.com

Lab Freaks Gone Wild?

Scientists plan to make “cybrids” by putting human DNA into cow eggs.The British government gave the go-ahead this week for two separate groups to experiment with the process. Scientists will “inject human DNA into empty eggs from cows, to create embryos known as cytoplasmic hybrids that are 99.9 per cent human in genetic terms,” according to The Times of London.

Read moreLab Freaks Gone Wild?