H/t reader kevin a.
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– New drug being developed using compound found in red wine ‘could help humans live until they are 150’ (Daily Mail March 10, 2013):
- Drugs are synthetic versions of resveratrol, found in red wine
- Research shows drugs which could prevent cancer and diabetes now viable
- Medication can be taken topically or orally
- No drugs yet developed to target aging skin
Drugs that could combat ageing and help people to live to 150-years-old may be available within five years, following landmark research.
The new drugs are synthetic versions of resveratrol which is found in red wine and is believed to have an anti-ageing effect as it boosts activity of a protein called SIRT1.
Pharmaceutical giant GlaxoSmithKline has been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease.
The work proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.
As each of the 117 drugs tested work on the single enzyme through a common mechanism is means that a whole new class of anti-ageing drugs is now viable, which could ultimately prevent cancer, Alzheimer’s disease and type 2 diabetes.
Genetics professor David Sinclair, based at Harvard University, said: ‘Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others.
‘In effect, they would slow ageing.’
The target enzyme, SIRT1, is switched on naturally by calorie restriction and exercise, but it can also be enhanced through activators.
Here are two excellent lists on what you can do to protect yourself from radiation:
Lugols solution is perfectly safe (this is also mentioned by another forum user in the following thread below) and a very good choice to protect yourself from radioactive iodine.
This is a further summary of radioprotective dietary supplements and other products that are available without a prescription. There are other products that are available by prescription, but I wanted to center on what people could fairly easily obtain.
The references following each entry on the list, for the most part are taken from peer reviewed scientific literature rather than from other sources, as I wanted to be as accurate as possible. Full articles are available from pubmed for a fee, but the abstracts are posted as they are free.
This list is supplied for those who wish to be proactive rather than counting on governmental institutions, so it is intended for those who are interested in what they personally can do to protect themselves and their family members from radioactive contamination.
The dosages listed are only suggestions, and many sources vary considerably as to dosage recommendations for a given product. In some instances the dosages given were those used to treat radiation victims.
Please be alert that doses for Adults and children may be radically different, and persons with health conditions such as kidney disease, liver disease, or other serious medical conditions should always consult with their personal health care provider before using any supplements. Also if you are pregnant or breastfeeding, discuss any supplements with your health care provider before using them.
(1) Probably most useful, (2) Potassium Iodide, Iodate and related products, (3) Vitamins, (4) Supplements, (5) Food items and (6) Miscellaneous products
(1) Probably most useful is here in the first post:
Pectin is found in large quantities in Apples and was used to detoxify radioactive Cesium from the children of Chernobyl. Dose for children was 5 grams twice daily during 18-25 day treatments.
“Twenty-two years after the Chernobyl releases, the annual individual dose limit in heavily contaminated territories of Belarus, Ukraine, and European Russia exceed 1 mSv/year just because of the unavoidable consumption of locally contaminated products.”
“For practical reasons the curative-like use of apple-pectin food additives might be especially helpful for effective decorporation of Cs-137. From 1996 to 2007 a total of more than 160,000 Belarussian children received pectin food additives during 18 to 25 days of treatment (5 g twice a day). As a result, levels of Cs-137 in children’s organs decreased after each course of pectin additives by an average of 30 to 40%.
Blocks uptake of stronium-90. Adults may take 1500 mg daily.
(either calcium alginate or sodium alginate) as an alternative treatment for radioactive strontium: “The data obtained show that the uptake of ingested strontium from milk was reduced by a factor of nine when alginate was added to milk. It is concluded that alginate preparations are a suitable antidote against radio-strontium.”
“A pilot production procedure has been established. Na alginate (sodium alginate) from S. siliquastrum (algae species)was proven to be a potent agent for reducing Sr (strontium) absorption, with high efficiency and virtually no toxicity. Strontium absorption in human subjects was reduced by 78% (+/- 8.9) or completely suppressed the increase of serum Sr at 2 h after ingestion. In cases of emergency, an alginate syrup preparation appears to be more suitable because of its rapid action.”
“It was found that administration of sodium alginate as a jelly overcomes the problem of constipation and effectively reduces Sr(89) uptake, up to 83%. This fact represents a significant finding with respect to the use of the compound in human subjects.”
Red wine may be much more potent than was thought in extending human lifespan, researchers say in a new report that is likely to give impetus to the rapidly growing search for longevity drugs.
The study is based on dosing mice with resveratrol, an ingredient of some red wines. Some scientists are already taking resveratrol in capsule form, but others believe it is far too early to take the drug, especially using wine as its source, until there is better data on its safety and effectiveness.
The report is part of a new wave of interest in drugs that may enhance longevity. On Monday, Sirtris, a startup founded in 2004 to develop drugs with the same effects as resveratrol, completed its sale to GlaxoSmithKline for $720 million.
Sirtris is seeking to develop drugs that activate protein agents known in people as sirtuins.
“The upside is so huge that if we are right, the company that dominates the sirtuin space could dominate the pharmaceutical industry and change medicine,” Dr. David Sinclair of the Harvard Medical School, a co-founder of the company, said Tuesday.
(And like always in these studies scientists want to isolate a miracle ingredient so that the corporations, “Big Pharma”, can sell it for a very high price and protect their profit monopole through a patent on it.
This the same completely backwards, unholistic approach that western medicine is using. An apple that has very little Vitamin C, but if you look at the synergy effect of those ingredients an apple is equivalent to 1500mg of Vitamin C! So trust nature.
And such News are always represented in an “Divide et Impera” way!
1-2 glasses Wine are just excellent for your health. – The Infinite Unknown)
NEW YORK — Is 90 the new 50?
Not yet, aging researchers say, but medical breakthroughs to significantly extend life and ease the ailments of getting older are closer than many people think.
“The general public has no idea what’s coming,” said David Sinclair, a Harvard Medical School professor who has made headlines with research into the health benefits of a substance found in red wine called resveratrol.
Speaking on a panel of aging experts, Sinclair had the boldest predictions. He said scientists can greatly increase longevity and improve health in lab animals like mice, and that drugs to benefit people are on the way.
“It’s not an if, but a when,” said Sinclair, who co-founded Sirtris Pharmaceuticals to pursue such drugs. The company, which is testing medicine in people with Type 2 diabetes, was recently bought for $720 million by GlaxoSmithKline, the world’s second-largest drug maker.